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  • GLASS FIBER LENGTH AND ORIENTATION ANALYSIS OF REINFORCED POLYMERS
    These fiber properties can be assessed using an X-ray scan at high resolution (µm scale). The results are obtained using a Bruker Skyscan 1272 (micro-CT) of Enabling Technologies set at a resolution of 2 µm per pixel. An oversized and offset scan have been applied to capture the whole USB connector at the desired resolution.
    At DSM, these results from the fiber property analysis are used to validate modelling techniques and supporting product and application development optimizing composition and processing conditions.

    Read full article @FEI.com

  • X-ray diffraction (XRD) is an ideal, non-destructive analytical method for examining all types of (semi-)crystalline samples. The newest equipment features alignment- and tool-free switching, with add-on possibilities for: 
    XRD at various temperatures (-190°C to 1600°C) / In-plane graze-incidence X-ray diffraction / X-ray reflectometry

    It offers a greatly improved low detec­tion limit. One can obtain information of the sample on e.g.:
    Phase identification/ Phase composition/ Crystal structure/ Microstructure

  • Steven Olde Damink, surgeon at MUMC+, is able to take big steps in characterizing biopsies of cancer patients. This thanks to the opening of the high-tech laboratories in Maastricht. Thanks to high resolution mass spectrometry, it is now possible to do detailed pathological research during surgeries. Read more in the Lab Magazine publications to be found below in this downloads/news page.
     
  • As Enabling Technologies we provide high-end analytical facilities and link unique analytical competencies of DSM Resolve and Maastricht University/UMC+ that promote innovation in the field of materials and life sciences. We strongly believe that science can change the world. For inspiration check the new video of DSM: https://www.youtube.com/watch?feature=player_embedded&v=Kfuc91MZchU
     
  • We have recently invested in new equipment! Have you ever seen images from a medical CT-scanner? Now, the same technique can be applied to your micro samples! With this Micro-CT you can analyse the particle features, pore features, homogeneity of distributions and visualize the internal structure in a 3D video or image. For more information please contact us.
     
  • NEWS: Dagblad de Limburger (vrijdag 27 februari 2015, blz. 14). Researchdirecteur Peter Borman van Sabic geeft aan: "Sabic is tevreden over de ontwikkeling van de Brightlands Chemelot Campus, waar alle soorten chemiebedrijven - klein en groot - en kennisinstellingen bij elkaar zitten. Het campusmodel helpt ons om mensen aan te trekken." Zijn onderzoekers maken ook gebruik van de kostbare apparatuur van Enabling Technologies die DSM Resolve op de Brightlands Chemelot Campus campus ter beschikking stelt aan derden, aldus Borman.

  • NEWS: Two top research groups have come to Maastricht and started the Maastricht Multimodal Molecular Imaging institute (M4I).
    In this institute Nanoscopy and Mass Spectrometry will be combined. With the mass microscope, researchers are able to directly, quickly and with precision determine in a single experiment the location and identity of thousands of molecules on cells and tissue samples. This diagnostic information is critical for personalized medicine, which is the healthcare of the future. With proper molecular information, medication can be prescribed to better meet the individual needs of patients. The medications that will or will not be effective can be determined at an early stage. This improves quality of life and reduces the cost of healthcare. This fundamental research is being further developed in Maastricht and informs clinical research, forensic research, research on cultural heritage and research on new smart biomaterials that are coming to light at the Chemelot Campus.
    The M4I Division of Nanoscopy investigates cell structures at a macromolecular level. Inside cells, proteins work together in complex structures and are responsible for virtually all processes in the human body, including diseases such as cancer. To understand the working mechanisms of protein complexes, three-dimensional imaging of normal and disease-causing protein complexes is essential. This could ultimately lead to more effective treatments, but also to vaccines against diseases such as tuberculosis. Using high-resolution cryo-electron microscopy, detailed photographs of complex protein structures in cells can be taken. Next, powerful computers transform these images into 3D structures of protein complexes. This technique requires painstaking preparation of the biological samples. To this end, the M4I Division of Nanoscopy has state-of-the-art microscopes at its disposal.

    Ron Heeren: https://www.youtube.com/watch?v=zHMxUKVcDXc
    Peter Peters: https://www.youtube.com/watch?v=Y5wvMPtYhSg
    Nanoscopy: http://www.maastrichtuniversity.nl/web/show/id=7014203/langid=42

  • One research group has come to Maastricht and started the MERLN Institute for Technology-Inspired Regenerative Medicine
    MERLN will strive for a leading position in the field of biomedical engineering by combining creative research with training of an interdisciplinary generation of scientists. MERLN’s activities operate at the interface of biology and engineering and aim at maximizing outreach at the level of public involvement, development and commercialization of research. MERLN’s vision is based on sharing of knowledge, infrastructure and ambition. Research at MERLN is focused on developing novel and challenging technologies to advance the field of tissue and organ repair and regeneration. The strategy involves, amongst others, the development of “smart” biomaterials which can trigger intrinsic tissue repair mechanisms mediated by the patient’s own cells. The primary focus of the research activities is on connective tissue repair and regeneration.

    Clemens van Blitterswijk: https://www.youtube.com/watch?v=HjYBwUS1eIO
    http://merln.maastrichtuniversity.nl/merln

     
     

  • NEWS: Seeing the Invisble : http://www.thepowerofimpossibility.com/blog/seeing-invisible/
    Article posted on the blog of Brightlands about the high-end microscope that was set up in the Institute of Nanoscopy of Maastricht University and offers the possibility to observe dynamic processes in living and fixed cells, as well as in histological sections. It provides a valuable toolbox for researchers at Brightlands Maastricht Health Campus, but also for third parties elsewhere. After all, Enabling Technologies offers open access to the STED (and other advanced) microscopes, which is unique for the Benelux.
    This development exemplifies that in the field of optical microscopy the Brightlands region is at the forefront of imaging in the Netherlands and the Euregion, its strength being a unique combination of microscopy: super-resolution, two-photon and spectral pathology (Nuance). This position is recognized in Europe. The fact that since the end of 2013, Maastricht is the only five star application & development EuroBioImaging site in the Netherlands may serve as proof.
    Prof. Marc van Zandvoort is the driver behind the advanced optical microscopy in Maastricht and he is extremely motivated to use his passion, expertise, and knowledge to embed the entire platform in the research community.   
     
  • NEWS: Nobel Price Chemistry 2014 for work in nanoscopy. The principe of the Stimulated Emission Depletion (STED) microscopy is rewarded. With STED two laser beams are utilized; one stimulates fluorescent molecules to glow, another cancels out all fluorescence except for that in a nanometre-sized volume. Scanning over the sample, nanometer for nanometer, yields an image with a resolution better than Abbe’s stipulated limit. Prof. dr. Marc van Zandvoort from the Maastricht University uses the STED eg for enriching insights in cardiovascular systems. Within Enabling Technologies we provide open access to such a STED microscope, see STED.
    For more information about the Nobel Price Chemistry 2014:
    Article on Nobel Price website
    Video on NU.nl
     
  • NEWS: Article on website of 'the power of impossibility'.
    Making the invisible visible, September 10, 2014
    Making the invisible visible and identifying what could not be identified. Brighlands Chemelot Campus and Maastricht Health Campus can offer academic and industrial researchers the very latest high-end equipment, thanks to the Enabling Technologies joint venture based on both campuses. Researchers need no longer purchase expensive analytical equipment themselves but can simply hire it for as long as they need it. The company hires out about 20 advanced microscopes, X-ray diffraction instruments, and mass and NMR spectrometers. These Rolls Royces among microscopes and spectrometers enable the analysis of highly complex chemical compounds.

    See http://www.thepowerofimpossibility.com/blog/makinginvisblevisible/ and https://www.facebook.com/thepowerofimpossibility?ref=hl for the full article.
     

  • CONFERENCE: Meet us as at the International Mass Spectrometry Conference in Geneva, August 24-29, 2014. We will present a poster about 'Resolving ionization processes of polyamides by ESI-IMS-MS'. For the poster see Facilities: UPLC-QTOF-MSMS

    Ion Mobility, coupled to Mass Spectrometry is an established tool for enhanced structural analysis of small and large molecules. Also for the analysis of synthetic polymers, the use of IMS-MS is increasing. In the poster we show the analysis of both low and high Mw polyamides with a new type of IMS-MS, the Bruker Trapped Ion Mobility Spectrometer (TIMS). This new type of analysis with its enhanced resolution and selectivity allows further insight into the ionization of polyamides and the presence of inter/intra molecular reaction products.
     

  • BROCHURES: New brochures can be downloaded: 'Easy access to high-end analytical equipment and expertise around the corner' and 'One portal to Open Joint Analytical Facilities for (bio)materials characterization'

    As an innovator in materials and/or life sciences, having access to high-end analytical tools might secure your road to success. However, these tools are hard to come by. They are expensive and often beyond your financial scope. Enabling Technologies hires out these facilities in our open Joint Facility Centre. You can hire them for just for a few hours or also include our expertise and training on how to use the equipment and how to interpret the results. Above all, we do this in an affordable way.
     

  • CONFERENCE: Meet us at 11th GCxGC Symposium, to be held in Riva del Garda, May 18-23, 2014. We will provide an oral presentation about 'Set-up a quantitative screening method of oxygen-containing compounds in petrochemicals by GCxGC'.

    Comprehensive analysis of oxygen containing compounds in petrochemical samples has become an intensive research topic for few years. These compounds can be found in various complex matrices such as conventional and bio-feedstocks, but also as by-products in process effluents of the petrochemical industry. They are often involved in fouling build-up, catalyst poisoning, corrosion issues or failed specification, hence the need of a proper identification of these species. The label “O-compounds” can cover a wide range of organic structures such as carboxylic acids, esters, ketones, cyclic or acyclic with various degrees of unsaturations as well as combinations with other heteroatoms (e.g. nitrogen, sulfur). Unlike N- or S- heteroatom containing compounds, no robust GC-detector is specific to O-containing molecules. However, the lack of specific detection can be compensated by a highly specific separation.
    The developed approach by using the GCxGC-QTOF of Enabling Technologies opened up new prospects for a generic quantitative screening of O-compounds in petrochemical samples. Identification of specific oxygenated molecules in specific effluents already gave some insights in their mechanism of formation.

    For the full abstract see Facilities: agilent-7200-q-tof-gcms-met-2d-gc-hrms-unit
     

  • CONFERENCE: Meet us at the 20th International Symposium on Analytical & Applied Pyrolysis, to be held in Birmingham UK, 19-23 May, 2014. We will present a poster 'Analysis of Biomass by Flash Pyrolysis Comprehensive Two-dimensional Gas Chromatography coupled to High Resolution QTOF MS'.

    Bio-oils contain valuable chemicals or from which valuable chemicals may be derived. For research purposes full detailed (group-type) characterization of biomass and/or bio-oils is often required. Comprehensive two-dimensional gas chromatography (GCxGC) is a powerful analytical technique for the analysis of truly complex samples such as pyrolysis bio-oils. In our work we apply online flash pyrolysis coupled to the GCxGC - high resolution QTOF mass spectrometry (Pyr-GCxGC-(EI/CI)-QTOF-MS) of Enabling Technologies for ultimate structure elucidation of bio-oil analytes.

    For the full abstract see Facilities: agilent-7200-q-tof-gcms-met-2d-gc-hrms-unit
     

  • NEWS (Dutch): Cristal Therapeutics, gevestigd op de Maastricht Health Campus, werkt aan nanomedicijnen waarmee ziektes zoals kanker gerichter en met minder bijwerkingen kunnen worden behandeld. Technomed Europe, gevestigd bij Maastricht-Aachen Airport, ontwierp een concentrische naald met een speciale coating die beter prikt, gemakkelijker glijdt en minder pijn bij de patiënt veroorzaakt. Beide bedrijven maken voor hun productontwikkelingen dankbaar gebruik van de specialistische en hoogwaardige apparatuur van Enabling Technologies: Nieuwsbrief_LEDBrainport2020.nl
     
  • CONFERENCE: Meet us on March 25 in Eindhoven at a microscopy conference: MikrocentrumProgramma
     
  • NEWS (Dutch): Maastricht UMC+ huisvest een imaging afdeling die tot de betere van Europa behoort, zo valt te lezen in het rapport van de Euro-BioImaging Expressions of Interest:  "De faciliteit werkt duidelijk op een baanbrekend niveau en biedt een unieke infrastructuur en mogelijkheden". Voor de imaging wordt onder andere gebruik gemaakt van afbeeldingstechnieken op allerlei niveaus zoals verschillende scans, optische (fluorescentie) en elektronen microscopie (o.a. van Enabling Technologies): Maastricht-UMC-beschikt-over-Europese-topfaciliteiten-voor-Bio-Imaging
     
  • VIDEO: For more videos go to our YouTube channel: http://www.youtube.com/user/enrichinginsights
     
  • PRESENTATION: November 2013 - Chemelot colloquium - Let’s innovate together by enriching our insights (pdf)
     
  • NEWS (Dutch): Om te groeien en zich verder te ontwikkelen, heeft een bedrijf innovaties nodig. Dat vergt veel onderzoek en dat kost geld. Grote bedrijven, universiteiten, maar ook het MKB in de regio doen al volop onderzoek op het gebied van materialen, life-sciences en chemie. Om dat onderzoek een extra impuls te geven, en daarmee regionale ontwikkeling te stimuleren, is Enabling Technologies opgericht. Enabling Technologies verhuurt kennis en dure onderzoeksapparatuur op basis van meettijd. Dat is vooral aantrekkelijk voor het MKB dat de hoge kosten voor de aanschaf van deze apparatuur niet zelf kan dragen. Op deze wijze maakt Enabling Technologies innovaties betaalbaar. Nieuwsbrief LEDBrainport2020.nl
     
  • NEWS (Dutch): NMR spectroscopie faciliteit Biochemie (CARIM) officieel geopend :  carimmaastricht.nl/nmr-spectroscopie-faciliteit
    Het betreft een state-of-the-art NMR (Nuclear Magnetic Resonance oftewel Nucleaire Magnetische Kernspin Resonantie) spectrometer van Bruker Biospin van Enabling Technologies, bedoeld voor het bestuderen van moleculen and eiwit structuren op atomaire resolutie. 
    Op de afdeling Biochemie en CARIM wordt onderzoek gedaan naar eiwitfactoren die betrokken bij bloedstolling en hart- en vaatziekten. De nieuwe 700 MHz NMR spectrometer is dan ook een welkome aanvulling op het repertoire van reeds aanwezige analytische technieken. Het kan worden gebruikt voor het gedetailleerd vaststellen van interacties tussen eiwitten, maar ook  voor het bepalen van interacties van eiwitten en nieuw ontwikkelde medicijnen, die belangrijk zijn in het voorkomen van trombose en hartinfarcten. Daarnaast biedt de NMR spectrometer ook de mogelijkheid spectra op te nemen van complexe mengsels zoals bloed- en urinemonsters van patienten om de samenstelling van lichaamsvreemde metabolieten in kaart te brengen. Een sterk veranderd NMR spectrum van een bloed- of urinemonster ten opzichte van een controlegroep is een diagnostische aanwijzing op een metabole ziekte of een indicatie van een mogelijke medische afwijking.  
     
  • VIDEO (Dutch): Kennis-as Limburg, rol Chemelot Campus en Maastricht Health Campus : Youtube_Kennis-As-Limburg
For the full abstract see Facilities: agilent-7200-q-tof-gcms-met-2d-gc-hrms-unit